Spatial mapping of RNA turnover kinetics in the mouse brain

Nature Neuroscience, Published online: 31 August 2026; doi:10.1038/s41593-026-02420-y

The authors developed spatial NT-seq to map the landscape of RNA turnover and stability regulation in the mouse brain, identifying the dentate gyrus as a turnover hotspot and revealing region-specific responses to electroconvulsive stimulation.