Behavioral adaptation to warm conditions via Lim1-mediated acceleration of neuronal clocks

Nature Neuroscience, Published online: 19 December 2025; doi:10.1038/s41593-025-02139-2

This study shows that animals can adapt behaviorally to warm environments by speeding up their internal clocks. Suprathreshold temperatures activate the Lim1 pathway in the fly brain, resulting in accelerated circadian clock activity and increased early morning activity.