Cerebral venous blood flow regulates intracerebral pressure and brain clearance via meningeal lymphatic vessels

Nature Neuroscience, Published online: 22 July 2026; doi:10.1038/s41593-026-02358-1

The authors show that cerebral venous blood flow and meningeal lymphatics co-regulate intracranial pressure and brain clearance in mice and humans. This finding supports idiopathic intracranial hypertension as a cerebral venous disorder.