Entorhinal cortex represents task-relevant remote locations independently of CA1

Nature Neuroscience, Published online: 01 April 2026; doi:10.1038/s41593-026-02232-0

Neurons in medial entorhinal cortex collectively represent discrete nonlocal positions during immobility. During this nonlocal coding, CA1 is uncoupled from entorhinal cortex. These representations are of task-relevant locations.