Convolutional neural network models describe the encoding subspace of local circuits in auditory cortex

Nature Neuroscience, Published online: 23 February 2026; doi:10.1038/s41593-026-02216-0

Wingert, Parida and colleagues measured tuning subspaces from deep-learning models trained on single neurons in auditory cortex. They show that subspaces distinguish functional properties between neuronal subtypes and describe a framework for sparse, efficient coding of natural sounds.